Palsy,Progressive Supranuclear

《英文msh詞典》Palsy,Progressive Supranuclear
[入口詞] Palsy,Progressive Supranuclear
[主題詞] Supranuclear Palsy,Progressive
[英文釋義] A degenerative disease of the central nervous system characterized by balance difficulties; OCULAR MOTILITY DISORDERS (supranuclear ophthalmoplegia); DYSARTHRIA; swallowing difficulties; and axial DYSTONIA. Onset is usually in the fifth decade and disease progression occurs over several years. Pathologic findings include neurofibrillary degeneration and neuronal loss in the dorsal MESENCEPHALON; SUBTHALAMIC NUCLEUS; RED NUCLEUS; pallidum; dentate nucleus; and vestibular nuclei. (From Adams et al.,Principles of Neurology,6th ed,pp1076-7)